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Journal: Scientific Reports
Article Title: Chitosan-dextran sulfate nanocapsules for enhanced tigecycline efficacy against non-typhoidal Salmonella enterica
doi: 10.1038/s41598-026-35229-7
Figure Lengend Snippet: TGC and/or unloaded CD NPs ameliorated the S. Typhimurium infected group induced histopathological alterations in mice’s liver tissues. Representative photomicrographs of the H&E-stained hepatic tissue sections showing the control (A), S. Typhimurium infected group (C), TGC (E), unloaded CD NPs (G), CD-TGC groups (I) and their respective higher magnifications (B, D, F, H, and J). A, B: control group displaying normal central vein (CV), hepatic cords (HC) with hepatocytes of eosinophilic granular cytoplasm (EC), rounded central single (SN) or double vesicular nuclei (DN), and kupffer cells (KC). C, D: S. Typhimurium infected group demonstrating multiple areas of variable-sized necrotic areas (NA) of coagulative necrosis (CN), severely dilated and congested sinusoid (SDS) with Kupffer cell hyperplasia (KCH). E, F: TGC group displaying moderately sized necrotic areas (MNA), moderately dilated and congested sinusoids (MDS), moderately hyperplastic Kupffer’s cells (MKC), interstitial mononuclear cell infiltration (MI), fibroblast proliferation (FP), and regenerated hepatocytes of stippling basophilic cytoplasm (BC) and pale nuclei (PN). G, H: unloaded CD NPs group showing a few scattered minute necrotic areas (mNA), intense mononuclear cell infiltration (IMI) around the portal area, and apparently normal hepatocytes (NH). I, J: CD-TGC group showed normal hepatocytes (NH), few dilated blood vessels (DBV), and a few interstitial lymphocytic aggregates (FL). Scale bars = 100 μm in A, C, E, G, I; and = 20 μm in B, D, F, H, and J. K: Bar charts demonstrate the statistical analysis of the comparative quantification of the hepatic injury scores in all studied groups. Bars carrying different superscript letters (a, b, c, d, and e) are significantly different as analyzed by the one-way ANOVA test, followed by the multiple comparisons by Duncan’s Post-hoc test ( p < 0.05). Values are the mean of 6 mice per group ± S.E.M.
Article Snippet:
Techniques: Infection, Staining, Control
Journal: International Journal of Molecular Sciences
Article Title: Green-Synthesized MgO Nanoparticles: Structural Insights and Antimicrobial Applications
doi: 10.3390/ijms26189021
Figure Lengend Snippet: Cytotoxicity assessment of green-synthesized MgO NPs after 4 days of incubation for ( a , c ) murine fibroblast L929 cells and ( b , d ) MG-63 osteoblast-like cells. The negative control consisted of cells incubated only with complete culture medium. Data are expressed as mean ± SD. Statistical analysis was performed using Student’s t -test (* p < 0.05, ** p ≤ 0.01, *** p ≤ 0.001).
Article Snippet: Immortalized murine fibroblast L929 cells,
Techniques: Synthesized, Incubation, Negative Control
Journal: International Journal of Molecular Sciences
Article Title: Green-Synthesized MgO Nanoparticles: Structural Insights and Antimicrobial Applications
doi: 10.3390/ijms26189021
Figure Lengend Snippet: Cytotoxicity assessment of green-synthesized MgO NPs after 7 days of incubation for ( a ) murine fibroblast L929 cells and ( b ) MG-63 osteoblast-like cells. The negative control consisted of cells incubated only with complete culture medium. Data are expressed as mean ± SD. Statistical analysis was performed using Student’s t -test (* p < 0.05, ** p ≤ 0.01, *** p ≤ 0.001).
Article Snippet: Immortalized murine fibroblast L929 cells,
Techniques: Synthesized, Incubation, Negative Control